KRT18P62

Across TCGA pan-cancer cohorts, KRT18P62 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated KRT18P62 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KRT18P62 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P62 expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

ACC, COAD, and BRCA are the cancer types where KRT18P62 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	II,III,IV	0.376	0.724	<.001	94	view →
COAD	OS	Tertile	All	0.876	0.759	.001	84	view →
BRCA	OS	Median	All	0.502	0.617	<.001	71	view →
KIRC	DFS	Quartile	IV	0.392	0.702	<.001	44	view →
UCEC	OS	Tertile	II,III,IV	0.782	0.882	.008	38	view →
GBM	DFS	Quartile	All	0.397	0.217	.001	35	view →
UVM	DFS	Tertile	III,IV	0.107	0.677	.004	27	view →
DLBC	DFS	Tertile	II,III,IV	0.065	0.829	<.001	27	view →
STAD	DFS	Median	IV	0.157	0.566	.003	18	view →
ESCA	OS	Tertile	III,IV	0.641	0.333	.021	17	view →
CESC	OS	Quartile	II,III,IV	0.584	0.799	.011	14	view →
THCA	DFS	Quartile	II,III,IV	0.716	0.894	.005	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

KRT18P62–ACC (DFS)

Open the ACC breakdown →