KRT18P61

Across TCGA pan-cancer cohorts, KRT18P61 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KRT18P61 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher KRT18P61 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P61 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CESC show a favorable association.

THCA, UCS, and KIRC are the cancer types where KRT18P61 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.833	0.946	<.001	89	view →
UCS	OS	Tertile	All	0.331	0.655	.002	66	view →
KIRC	DFS	Median	IV	0.247	0.582	.010	51	view →
UCEC	DFS	Median	All	0.922	0.872	.009	42	view →
KICH	OS	Tertile	III,IV	0.309	0.906	.003	27	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	18	view →
CESC	DFS	Median	IV	0.471	0.091	.013	12	view →
HNSC	OS	Quartile	II,III,IV	0.676	0.780	.017	11	view →
ESCA	OS	Median	All	0.617	1.000	.009	11	view →
SKCM	OS	Tertile	III,IV	1.000	0.771	.001	9	view →
THYM	DFS	Quartile	All	0.767	0.938	.013	9	view →
MESO	OS	Median	II,III,IV	0.716	0.330	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

KRT18P61–THCA (DFS)

Open the THCA breakdown →