KRT18P50

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KRT18P50 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated KRT18P50 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher KRT18P50 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT18P50 expression acts as an unfavorable survival marker, although some lineages such as COAD and LGG show a favorable association.

UCS, LIHC, and THCA are the cancer types where KRT18P50 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSOSTertileII,III,IV0.0850.648<.00190view →
LIHCOSTertileAll0.2090.527<.00181view →
THCADFSTertileIII,IV0.6540.851.00378view →
BRCAOSTertileII,III,IV0.4320.573.00160view →
KIRPDFSTertileII,III,IV0.0400.765<.00136view →
COADOSTertileII,III,IV0.9850.834.02430view →
ESCAOSTertileII,III,IV0.1040.926<.00127view →
LGGOSTertileAll0.9560.872.00121view →
SKCMOSTertileIII,IV0.2550.840<.00118view →
CESCDFSTertileIII,IV0.2400.726.01518view →
LUSCDFSTertileIII,IV0.0790.751.02418view →
PAADOSTertileAll0.2830.598.0059view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration