Across TCGA pan-cancer cohorts, KRT18P44 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KRT18P44’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where KRT18P44 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT18P44 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
STAD, LUAD, and HNSC are the cancer types where KRT18P44 tumor–normal differential expression is most reproducible.