KRT18P43

Across TCGA pan-cancer cohorts, KRT18P43 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of KRT18P43’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where KRT18P43 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT18P43 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

COAD, STAD, and PAAD are the cancer types where KRT18P43 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT18P43 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+0.116	.007	8	view →
STAD	All	All	+0.069	.008	4	view →
PAAD	Male	All	−0.075	.004	2	view →
PRAD	All	All	+0.020	.004	2	view →
HNSC	Male	II,III,IV	+0.020	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

KRT18P43–COAD

Open the COAD breakdown →