KRT18P41

Across TCGA pan-cancer cohorts, KRT18P41 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated KRT18P41 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher KRT18P41 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P41 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

SKCM, LUAD, and KIRC are the cancer types where KRT18P41 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	II,III,IV	0.272	0.580	<.001	54	view →
LUAD	OS	Tertile	All	0.739	0.842	.002	50	view →
KIRC	DFS	Median	III,IV	0.834	0.683	.001	39	view →
HNSC	OS	Quartile	IV	0.826	0.587	.004	39	view →
LUSC	OS	Tertile	IV	0.057	0.786	.008	36	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	36	view →
LAML	DFS	Quartile	All	0.298	0.516	.007	34	view →
PAAD	DFS	Tertile	All	0.222	0.425	.003	29	view →
CESC	OS	Quartile	All	0.958	0.840	.006	18	view →
ACC	DFS	Tertile	III,IV	0.048	0.457	.015	18	view →
KIRP	DFS	Median	All	0.602	0.911	.003	16	view →
GBM	OS	Tertile	All	0.086	0.415	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

KRT18P41–SKCM (DFS)

Open the SKCM breakdown →