KRT18P40

Across TCGA pan-cancer cohorts, KRT18P40 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated KRT18P40 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher KRT18P40 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT18P40 expression acts as an unfavorable survival marker, although some lineages such as KIRP and GBM show a favorable association.

LUAD, KIRC, and STAD are the cancer types where KRT18P40 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.453	0.626	<.001	99	view →
KIRC	DFS	Quartile	All	0.517	0.686	<.001	60	view →
STAD	OS	Median	IV	0.194	0.642	.003	49	view →
DLBC	OS	Tertile	III,IV	0.260	1.000	.002	37	view →
ESCA	OS	Median	All	0.605	0.782	.005	33	view →
KIRP	DFS	Median	IV	0.595	0.037	.001	30	view →
THYM	DFS	Quartile	All	0.757	0.917	.005	27	view →
LUSC	DFS	Quartile	All	0.248	0.551	<.001	26	view →
SKCM	DFS	Tertile	IV	0.055	0.515	.005	21	view →
GBM	DFS	Quartile	All	0.455	0.191	.002	18	view →
OV	DFS	Tertile	IV	0.598	0.349	.011	18	view →
THCA	OS	Tertile	IV	0.593	0.940	.010	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

KRT18P40–LUAD (OS)

Open the LUAD breakdown →