Across TCGA pan-cancer cohorts, KRT18P27 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated KRT18P27 data layer.
The strongest signal is observed in brain lower grade glioma (LGG), where higher KRT18P27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P27 expression acts as an unfavorable survival marker, although some lineages such as CESC and PRAD show a favorable association.
LGG, ACC, and THYM are the cancer types where KRT18P27 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.