KRT18P18

Across TCGA pan-cancer cohorts, KRT18P18 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KRT18P18 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher KRT18P18 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P18 expression acts as an unfavorable survival marker, although some lineages such as LIHC and BRCA show a favorable association.

LUAD, UCEC, and DLBC are the cancer types where KRT18P18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.457	0.621	.001	56	view →
UCEC	DFS	Median	IV	0.348	0.743	.004	44	view →
DLBC	DFS	Tertile	IV	0.120	0.683	.001	36	view →
LIHC	OS	Tertile	II,III,IV	0.770	0.380	<.001	27	view →
LUSC	DFS	Median	II,III,IV	0.487	0.786	.008	19	view →
OV	OS	Quartile	All	0.624	0.735	.010	18	view →
SARC	DFS	Tertile	All	0.452	0.631	.010	18	view →
TGCT	DFS	Quartile	All	0.686	0.882	.020	16	view →
ESCA	OS	Median	All	0.440	1.000	.008	15	view →
MESO	OS	Tertile	IV	0.363	0.757	.013	14	view →
BRCA	DFS	Tertile	III,IV	0.936	0.822	.003	12	view →
SKCM	OS	Tertile	III,IV	0.139	0.396	.029	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

KRT18P18–LUAD (DFS)

Open the LUAD breakdown →