KRT18P17

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KRT18P17 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KRT18P17 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher KRT18P17 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT18P17 expression acts as an unfavorable survival marker, although some lineages such as KIRP and KIRC show a favorable association.

LUAD, LIHC, and KIRP are the cancer types where KRT18P17 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSTertileAll0.2470.510<.00163view →
LIHCOSTertileAll0.6500.852<.00146view →
KIRPDFSMedianIV0.8120.041<.00138view →
KIRCDFSMedianII,III,IV0.8520.654.00922view →
PAADOSMedianII,III,IV0.5120.656.00820view →
UVMDFSQuartileII,III,IV0.7860.449.00920view →
ACCDFSTertileAll0.5120.825.01418view →
OVDFSMedianIII,IV0.3310.407.01818view →
LGGOSQuartileAll0.8270.926.00215view →
GBMDFSMedianAll0.1820.366.00915view →
ESCAOSMedianAll0.6471.000.01513view →
MESODFSMedianAll0.5880.302.02012view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration