Across TCGA pan-cancer cohorts, KRT18P12 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KRT18P12’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KRT18P12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT18P12 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, STAD, and ESCA are the cancer types where KRT18P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT18P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.015	.005	7	view →
STAD	All	All	+0.062	.005	3	view →
ESCA	All	II,III,IV	+0.090	.012	2	view →
THCA	Female	All	−0.013	.002	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: KRT18P12 RNA expression & survival · all KRT18P12 data types