Across TCGA patient cohorts, KRT17P7 mutation is significantly associated with the RNA expression of many other genes, with 453 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT17P7-associated genes across cancer lineages are SRXN1, PRODH, and PACSIN2. Each is linked with KRT17P7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT17P7-to-partner and partner-to-KRT17P7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT17P7→partner) and Y-score (partner→KRT17P7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SRXN1 →	+0.800	+3.375	<.001	.005	3	1
UCEC	PRODH →	+1.664	+3.364	<.001	.005	3	1
UCEC	PACSIN2 →	+0.927	+3.343	<.001	.005	3	1
UCEC	MTHFD1 →	+0.789	+3.332	<.001	.005	3	1
UCEC	SLCO4A1 →	+1.574	+3.332	<.001	.005	3	1
UCEC	AAGAB →	+0.557	+3.364	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 453 associations by consensus.

Exploration

KRT17P7 survival (RNA) · tumor vs normal (RNA) · all KRT17P7 data types