KRT17

Across TCGA cell cohorts, KRT17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,954 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible KRT17-associated GO terms across cancer lineages are Positive regulation of cytoplasmic translation, Regulation of protein localization to nucleus, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with KRT17 in more than 11 cancer types. Because this analysis shows association rather than direction, both KRT17-to-partner and partner-to-KRT17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoplasmic translation grouped by KRT17-low versus KRT17-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT17→partner) and Y-score (partner→KRT17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of cytoplasmic translation →	+0.129	+3.014	<.001	<.001	3	12
OVARY	Regulation of protein localization to nucleus →	+0.061	+2.353	.001	.008	2	12
LARGE_INTESTINE	Regulation of ubiquitin-dependent protein catabolic process →	+0.061	+3.012	<.001	.001	3	11
URINARY_TRACT	Regulation of hair follicle development →	+0.268	+5.249	<.001	<.001	3	10
BREAST	Regulation of protein modification by small protein conjugation or removal →	+0.063	+3.542	<.001	.002	3	10
PANCREAS	Positive regulation of protein import into nucleus →	+0.114	+5.508	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,954 associations by consensus.

Positive regulation of cytoplasmic translation by KRT17 expression — OVARY

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