KRT17

Across TCGA cell cohorts, KRT17 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible KRT17-associated genes across cancer lineages are CSNKA2IP, C7orf33, and KRTAP13-2. Each is linked with KRT17 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT17-to-partner and partner-to-KRT17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSNKA2IP grouped by KRT17-low versus KRT17-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT17→partner) and Y-score (partner→KRT17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CSNKA2IP →	+0.006	+4.672	<.001	.002	3	2
OVARY	C7orf33 →	+0.039	+3.990	<.001	.003	3	2
SOFT_TISSUE	KRTAP13-2 →	+0.017	+4.977	<.001	.002	3	1
SOFT_TISSUE	KRTAP17-1 →	+0.011	+4.369	<.001	.008	3	1
SOFT_TISSUE	GPX6 →	+0.017	+4.369	<.001	.008	3	1
SOFT_TISSUE	GOLGA6L6 →	+0.009	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

CSNKA2IP by KRT17 expression — BREAST

Explore this box plot interactively →