Across TCGA patient cohorts, KRT16 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,975 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT16-associated proteins across cancer lineages are ANXA1, JUNB, and KRT6A. Each is linked with KRT16 in more than 7 cancer types. Because this analysis shows association rather than direction, both KRT16-to-partner and partner-to-KRT16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT16→partner) and Y-score (partner→KRT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANXA1 →	+0.560	+1.453	<.001	<.001	3	8
LSCC	JUNB →	+0.456	+2.527	<.001	<.001	3	8
COAD	KRT6A →	+2.338	+1.578	<.001	.001	3	8
UCEC	TRIM29 →	+1.298	+2.597	<.001	<.001	3	7
PDAC	TRIM29_S489 →	+1.397	+1.467	<.001	<.001	3	7
GBM	ANXA2 →	+0.521	+0.552	.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,975 associations by consensus.

Exploration

KRT16 survival (RNA) · tumor vs normal (RNA) · all KRT16 data types