Across TCGA patient cohorts, KRT16 protein abundance is significantly associated with the RNA expression of many other genes, with 14,597 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT16-associated genes across cancer lineages are KRT14, KRT6A, and PERP. Each is linked with KRT16 in more than 6 cancer types. Because this analysis shows association rather than direction, both KRT16-to-partner and partner-to-KRT16 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT16→partner) and Y-score (partner→KRT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KRT14 →	+3.888	+1.622	<.001	<.001	3	7
PDAC	KRT6A →	+3.528	+1.636	<.001	<.001	3	7
BRCA	PERP →	+0.948	+1.445	<.001	<.001	3	6
LSCC	SLC2A1 →	+1.033	+1.283	<.001	<.001	3	6
BRCA	TRIM29 →	+1.583	+1.358	<.001	<.001	3	6
HNSC	GSDMC →	+1.374	+1.440	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,597 associations by consensus.

Exploration

KRT16 survival (RNA) · tumor vs normal (RNA) · all KRT16 data types