Across TCGA cell cohorts, KRT16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,413 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible KRT16-associated GO terms across cancer lineages are Cell-substrate junction assembly, Antimicrobial peptide production, and Antimicrobial peptide biosynthetic process. Each is linked with KRT16 in more than 11 cancer types. Because this analysis shows association rather than direction, both KRT16-to-partner and partner-to-KRT16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT16→partner) and Y-score (partner→KRT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.158	+1.731	<.001	<.001	3	11
BREAST	Antimicrobial peptide production →	+1.318	+3.047	<.001	<.001	3	11
BREAST	Antimicrobial peptide biosynthetic process →	+1.318	+3.047	<.001	<.001	3	11
BREAST	Antibacterial peptide production →	+1.318	+3.047	<.001	<.001	3	11
BREAST	Antibacterial peptide biosynthetic process →	+1.318	+3.047	<.001	<.001	3	11
BREAST	Cellular response to steroid hormone stimulus →	+0.067	+3.142	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,413 associations by consensus.

Exploration

KRT16 survival (RNA) · tumor vs normal (RNA) · all KRT16 data types