KRT15

Across TCGA pan-cancer cohorts, KRT15 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KRT15 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher KRT15 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KRT15 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

GBM, HNSC, and LUAD are the cancer types where KRT15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.173	0.746	.038	3	view →
HNSC	OS	Median	IV	0.600	0.827	.021	1	view →
LUAD	OS	Quartile	All	1.000	0.933	.035	1	view →
PDAC	DFS	Quartile	II,III,IV	0.611	0.937	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KRT15–GBM (OS)

Open the GBM breakdown →