Across TCGA pan-cancer cohorts, KRT14 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRT14 data layer compared with 24 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KRT14 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KRT14 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, LSCC, and PDAC are the cancer types where KRT14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	1.000	0.906	.006	29	view →
LSCC	DFS	Median	All	0.976	0.891	.003	13	view →
PDAC	OS	Quartile	III,IV	0.281	0.802	.011	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KRT14 tumor-vs-normal RNA expression · all KRT14 data types