Across TCGA patient cohorts, KRT14 RNA expression is significantly associated with the RNA expression of many other genes, with 11,926 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible KRT14-associated genes across cancer lineages are KRT16, KRT17, and KRT6A. Each is linked with KRT14 in more than 28 cancer types. Because this analysis shows association rather than direction, both KRT14-to-partner and partner-to-KRT14 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT14→partner) and Y-score (partner→KRT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	KRT16 →	+6.564	+8.228	<.001	<.001	3	29
ESCA	KRT17 →	+4.549	+7.479	<.001	<.001	3	28
ESCA	KRT6A →	+8.041	+8.215	<.001	<.001	3	25
ESCA	KRT6B →	+6.213	+7.734	<.001	<.001	3	25
ESCA	KRT5 →	+7.805	+7.876	<.001	<.001	3	24
ESCA	SERPINB5 →	+2.294	+5.868	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,926 associations by consensus.

Exploration

KRT14 survival (RNA) · tumor vs normal (RNA) · all KRT14 data types