Across TCGA cell cohorts, KRT14 mutation is significantly associated with the RNA expression of many other genes, with 287 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRT14-associated genes across cancer lineages are KRT76, KRTAP4-4, and FIGLA. Each is linked with KRT14 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT14-to-partner and partner-to-KRT14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT14→partner) and Y-score (partner→KRT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	KRT76 →	+0.026	+4.011	<.001	.009	3	2
URINARY_TRACT	KRTAP4-4 →	+0.016	+3.459	<.001	.002	3	2
BREAST	FIGLA →	+0.203	+4.421	.003	.004	3	2
LARGE_INTESTINE	DAZ2 →	+0.252	+4.415	<.001	.007	3	2
OESOPHAGUS	UGT2B10 →	+0.025	+4.437	.001	<.001	3	1
OESOPHAGUS	AKAIN1 →	+0.047	+3.432	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 287 associations by consensus.

Exploration

KRT14 survival (RNA) · tumor vs normal (RNA) · all KRT14 data types