KRT13

Across TCGA patient cohorts, KRT13 mutation is significantly associated with the RNA expression of many other genes, with 2,341 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT13-associated genes across cancer lineages are HMGB3P3, MAP1LC3P, and KHSRP. Each is linked with KRT13 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT13-to-partner and partner-to-KRT13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGB3P3 grouped by KRT13-low versus KRT13-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT13→partner) and Y-score (partner→KRT13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	HMGB3P3 →	+0.173	+4.952	<.001	.002	3	3
KIRP	MAP1LC3P →	+0.395	+5.016	<.001	.002	3	3
UCEC	KHSRP →	+0.505	+2.136	<.001	.002	3	3
LUSC	RN7SL847P →	+0.311	+5.337	<.001	.006	3	3
GBM	SERF1AP1 →	+0.316	+4.651	<.001	.003	3	2
LGG	OR11H1 →	+0.044	+7.977	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,341 associations by consensus.

HMGB3P3 by KRT13 expression — KIRP

Explore this box plot interactively →