KRT13

Across TCGA cell cohorts, KRT13 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT13-associated genes across cancer lineages are TNP1, LCE1C, and SLC5A8. Each is linked with KRT13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT13-to-partner and partner-to-KRT13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by KRT13-low versus KRT13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT13→partner) and Y-score (partner→KRT13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.128	+4.415	<.001	.007	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CFHR2 →	+0.395	+5.539	<.001	.003	3	1
SKIN	OR5T1 →	+0.019	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TNP1 by KRT13 expression — LARGE_INTESTINE

Explore this box plot interactively →