Across TCGA pan-cancer cohorts, KRT127P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of KRT127P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KRT127P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT127P is over-expressed in tumor.
HNSC are the cancer types where KRT127P tumor–normal differential expression is most reproducible.