Across TCGA patient cohorts, KRT12 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,928 significant associations in total. THYM shows the largest number of these associations.

The most reproducible KRT12-associated GO terms across cancer lineages are ER-nucleus signaling pathway, Golgi organization, and Vesicle-mediated transport to the plasma membrane. Each is linked with KRT12 in more than 16 cancer types. Because this analysis shows association rather than direction, both KRT12-to-partner and partner-to-KRT12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT12→partner) and Y-score (partner→KRT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ER-nucleus signaling pathway →	+0.086	+0.226	<.001	<.001	3	17
UVM	Golgi organization →	+0.043	+0.029	<.001	<.001	3	16
THYM	Vesicle-mediated transport to the plasma membrane →	+0.037	+0.158	<.001	<.001	3	16
UVM	Mitochondrial membrane organization →	+0.033	+0.038	<.001	<.001	3	15
THYM	Neural tube development →	+0.039	+0.146	<.001	<.001	3	15
THYM	Obsolete ubiquitin-dependent ERAD pathway →	+0.051	+0.159	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,928 associations by consensus.

Exploration

KRT12 survival (RNA) · tumor vs normal (RNA) · all KRT12 data types