Across TCGA patient cohorts, KRT12 mutation is significantly associated with the RNA expression of many other genes, with 1,918 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT12-associated genes across cancer lineages are MBD3L5, MIR4659A, and NF1P10. Each is linked with KRT12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT12-to-partner and partner-to-KRT12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT12→partner) and Y-score (partner→KRT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MBD3L5 →	+0.084	+4.984	<.001	.003	3	2
CESC	MIR4659A →	+0.517	+4.166	.003	.004	3	2
CESC	NF1P10 →	+0.096	+4.984	.003	.003	3	2
CESC	RNVU1-33 →	+0.246	+3.816	<.001	.007	3	2
CESC	LINC02476 →	+0.471	+3.934	<.001	.005	3	2
CESC	LINC02708 →	+0.070	+4.559	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,918 associations by consensus.

Exploration

KRT12 survival (RNA) · tumor vs normal (RNA) · all KRT12 data types