Across TCGA cell cohorts, KRT12 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,468 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KRT12-associated GO terms across cancer lineages are Regulation of actin filament polymerization, B cell apoptotic process, and Positive regulation of cytokine-mediated signaling pathway. Each is linked with KRT12 in more than 4 cancer types. Because this analysis shows association rather than direction, both KRT12-to-partner and partner-to-KRT12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT12→partner) and Y-score (partner→KRT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of actin filament polymerization →	+0.078	+0.365	<.001	.004	3	5
KIDNEY	B cell apoptotic process →	+0.163	+0.122	.001	.002	3	4
BREAST	Positive regulation of cytokine-mediated signaling pathway →	+0.058	+0.103	.002	.004	3	4
OESOPHAGUS	Regulation of CD8-positive, alpha-beta T cell proliferation →	+0.172	+0.163	<.001	.007	3	4
BREAST	Negative regulation of response to biotic stimulus →	+0.068	+0.119	.001	<.001	3	4
SKIN	Signal transduction in absence of ligand →	+0.111	+0.368	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,468 associations by consensus.

Exploration

KRT12 survival (RNA) · tumor vs normal (RNA) · all KRT12 data types