Across TCGA patient cohorts, KRT10 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,504 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KRT10-associated proteins across cancer lineages are UTP25, PSME3, and FBP1. Each is linked with KRT10 in more than 4 cancer types. Because this analysis shows association rather than direction, both KRT10-to-partner and partner-to-KRT10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT10→partner) and Y-score (partner→KRT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UTP25 →	+0.359	+0.940	<.001	<.001	3	5
LSCC	PSME3 →	+0.278	+0.597	<.001	.001	3	5
PDAC	FBP1 →	-0.562	-0.546	.001	.001	3	5
LSCC	RCSD1 →	-0.522	-0.760	<.001	<.001	3	4
BRCA	SEC11C →	-0.865	-0.682	<.001	<.001	3	4
LSCC	LIG3 →	+0.446	+0.612	<.001	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,504 associations by consensus.

Exploration

KRT10 survival (RNA) · tumor vs normal (RNA) · all KRT10 data types