KRT1

Across TCGA cell cohorts, KRT1 RNA expression is significantly associated with the RNA expression of many other genes, with 2,687 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT1-associated genes across cancer lineages are KRT74, KRT2, and KRT77. Each is linked with KRT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KRT1-to-partner and partner-to-KRT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT1 versus KRT74 in BLOOD_Leukemia, with a Pearson correlation of 0.68.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT1→partner) and Y-score (partner→KRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KRT74 →	+0.234	+1.670	.001	<.001	2	5
BLOOD_Leukemia	KRT2 →	+0.414	+0.808	<.001	<.001	3	3
URINARY_TRACT	KRT77 →	+0.490	+1.517	.002	.006	1	5
UPPER_AERODIGESTIVE_TRACT	SERPINB13 →	+3.131	+3.009	<.001	<.001	2	4
UPPER_AERODIGESTIVE_TRACT	KRT6C →	+2.220	+2.318	<.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	SLURP2 →	+3.059	+2.576	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,687 associations by consensus.

KRT1 vs KRT74 — BLOOD_Leukemia

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