KRIT1

Across TCGA patient cohorts, KRIT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,301 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KRIT1-associated proteins across cancer lineages are MEPCE, PEX1, and PUS7. Each is linked with KRIT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KRIT1-to-partner and partner-to-KRIT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRIT1 versus MEPCE in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRIT1→partner) and Y-score (partner→KRIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MEPCE →	+0.338	+0.748	<.001	<.001	3	6
LSCC	PEX1 →	+0.317	+0.509	<.001	<.001	3	5
HNSC	PUS7 →	+0.443	+0.587	<.001	<.001	3	5
PDAC	WASL →	+0.363	+0.283	<.001	.001	3	5
LUAD	GTF2I →	+0.346	+0.463	<.001	<.001	3	5
HNSC	RSBN1L →	+0.404	+0.729	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,301 associations by consensus.

KRIT1 vs MEPCE — HNSC

Explore this scatter interactively →