KRI1

Across TCGA patient cohorts, KRI1 mutation is significantly associated with the RNA expression of many other genes, with 1,107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRI1-associated genes across cancer lineages are RNF19BPY, RNA5SP90, and RNY1P2. Each is linked with KRI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRI1-to-partner and partner-to-KRI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF19BPY grouped by KRI1-low versus KRI1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRI1→partner) and Y-score (partner→KRI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNF19BPY →	+0.009	+7.473	<.001	.007	3	3
HNSC	RNA5SP90 →	+0.217	+3.176	<.001	.009	3	2
HNSC	RNY1P2 →	+0.139	+4.547	<.001	.004	3	2
HNSC	MIR1208 →	+0.380	+3.226	<.001	.009	3	2
PRAD	MIR448 →	+0.283	+7.939	<.001	.008	3	2
BLCA	MTCO3P45 →	+0.027	+3.051	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,107 associations by consensus.

RNF19BPY by KRI1 expression — BRCA

Explore this box plot interactively →