KREMEN2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KREMEN2 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KREMEN2-associated genes across cancer lineages are CD4+ Tem. Each is linked with KREMEN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KREMEN2-to-partner and partner-to-KREMEN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by KREMEN2-low versus KREMEN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KREMEN2→partner) and Y-score (partner→KREMEN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMCD4+ Tem →+0.034+5.624<.001.03931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tem by KREMEN2 expression — SKCM

Box plot of CD4+ Tem in KREMEN2-low vs KREMEN2-high samples in SKCM.

Explore this box plot interactively →

Exploration