KREMEN2

Across TCGA cell cohorts, KREMEN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,502 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KREMEN2-associated GO terms across cancer lineages are rRNA transcription, Positive regulation of fibrinolysis, and Positive regulation of hemostasis. Each is linked with KREMEN2 in more than 11 cancer types. Because this analysis shows association rather than direction, both KREMEN2-to-partner and partner-to-KREMEN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA transcription grouped by KREMEN2-low versus KREMEN2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KREMEN2→partner) and Y-score (partner→KREMEN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	rRNA transcription →	+0.101	+0.983	.001	.004	2	12
LUNG_SCLC	Positive regulation of fibrinolysis →	+1.052	+0.948	<.001	.002	3	10
LIVER	Positive regulation of hemostasis →	-0.239	-1.441	.001	.002	3	9
OVARY	Regulation of phospholipid efflux →	+0.922	+1.475	<.001	<.001	3	9
OVARY	Positive regulation of phospholipid efflux →	+0.922	+1.475	<.001	<.001	3	9
LIVER	Positive regulation of blood coagulation →	-0.239	-1.441	.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,502 associations by consensus.

rRNA transcription by KREMEN2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →