KRCC1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KRCC1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated KRCC1 data layer compared with 25 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher KRCC1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRCC1 expression acts as an unfavorable survival marker.

OV are the cancer types where KRCC1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVOSMedianII,III,IV0.0760.844<.00148view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

KRCC1–OV (OS)

Kaplan–Meier survival curve for KRCC1 mutant vs wild-type samples in OV.

Open the OV breakdown →

Exploration