KRCC1

Across TCGA cell cohorts, KRCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,469 significant associations in total. CNS shows the largest number of these associations.

The most reproducible KRCC1-associated GO terms across cancer lineages are Negative regulation of stress granule assembly, Vesicle budding from membrane, and Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with KRCC1 in more than 12 cancer types. Because this analysis shows association rather than direction, both KRCC1-to-partner and partner-to-KRCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stress granule assembly grouped by KRCC1-low versus KRCC1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRCC1→partner) and Y-score (partner→KRCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of stress granule assembly →	+0.117	+1.293	<.001	.001	3	13
URINARY_TRACT	Vesicle budding from membrane →	+0.078	+1.731	.001	<.001	3	12
BONE	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.162	-1.395	<.001	<.001	3	12
BLOOD_Myeloma	Macroautophagy →	+0.049	+1.203	.006	.006	3	11
BONE	Positive regulation of G2/MI transition of meiotic cell cycle →	-0.158	-1.255	<.001	<.001	3	11
OESOPHAGUS	Process utilizing autophagic mechanism →	+0.067	+1.451	.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,469 associations by consensus.

Negative regulation of stress granule assembly by KRCC1 expression — URINARY_TRACT

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