Across TCGA patient cohorts, KRBA2 mutation is significantly associated with the RNA expression of many other genes, with 1,380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRBA2-associated genes across cancer lineages are MIR549A, RNA5SP223, and RN7SL794P. Each is linked with KRBA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRBA2-to-partner and partner-to-KRBA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRBA2→partner) and Y-score (partner→KRBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR549A →	+0.341	+5.147	<.001	.003	3	2
UCEC	RNA5SP223 →	+0.176	+3.079	<.001	.006	3	2
UCEC	RN7SL794P →	+0.245	+1.754	<.001	.007	3	2
UCEC	LINC02742 →	+0.074	+1.754	.001	.006	3	2
UCEC	RNU6-718P →	+0.129	+3.374	.001	.003	3	2
SKCM	MIR8053 →	+0.266	+4.328	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,380 associations by consensus.

Exploration

KRBA2 survival (RNA) · tumor vs normal (RNA) · all KRBA2 data types