Across TCGA patient cohorts, KRBA2 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRBA2-associated genes across cancer lineages are ERK2, Cyclin-B1, and eIF4E. Each is linked with KRBA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRBA2-to-partner and partner-to-KRBA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRBA2→partner) and Y-score (partner→KRBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.214	+1.700	.008	.044	3	2
UCEC	Cyclin-B1 →	+0.716	+2.906	.002	.001	3	2
UCEC	eIF4E →	+0.209	+3.183	.019	.009	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.592	+1.700	.006	.044	3	1
UCEC	INPP4B →	-0.391	-3.584	.004	.002	3	1
UCEC	JNK2 →	+0.204	+2.834	.015	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

KRBA2 survival (RNA) · tumor vs normal (RNA) · all KRBA2 data types