KRBA1

Across TCGA patient cohorts, KRBA1 mutation is significantly associated with the RNA expression of many other genes, with 3,129 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRBA1-associated genes across cancer lineages are B3GNT4, RN7SL824P, and H2BC13. Each is linked with KRBA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRBA1-to-partner and partner-to-KRBA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B3GNT4 grouped by KRBA1-low versus KRBA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRBA1→partner) and Y-score (partner→KRBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	B3GNT4 →	+0.384	+2.280	.001	<.001	3	3
COAD	RN7SL824P →	+0.125	+4.028	<.001	.001	3	3
UCEC	H2BC13 →	+0.505	+1.847	.001	<.001	3	3
UCEC	FANCA →	+0.567	+3.108	<.001	<.001	3	3
SKCM	LINC02585 →	+0.762	+3.006	<.001	<.001	3	3
COAD	RNA5SP363 →	+0.596	+3.567	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,129 associations by consensus.

B3GNT4 by KRBA1 expression — UCEC

Explore this box plot interactively →