KPTN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KPTN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,669 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KPTN-associated proteins across cancer lineages are PRMT1, CSTF3, and HSPBP1. Each is linked with KPTN in more than 5 cancer types. Because this analysis shows association rather than direction, both KPTN-to-partner and partner-to-KPTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPTN versus PRMT1 in GBM, with a Pearson correlation of 0.22.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KPTN→partner) and Y-score (partner→KPTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPRMT1 →+0.353+0.463.001.00736
GBMCSTF3 →+0.272+0.455<.001<.00135
HNSCHSPBP1 →+0.275+0.592<.001<.00134
GBMLIG1_S76 →+0.807+0.611<.001<.00134
LUADLMNA_S277 →-0.638-0.429<.001.00134
GBMSTRN4 →+0.288+0.688<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,669 associations by consensus.

KPTN vs PRMT1 — GBM

Per-sample scatter of KPTN vs PRMT1 in GBM (Pearson r = 0.22).

Explore this scatter interactively →

Exploration