KPTN

Across TCGA patient cohorts, KPTN protein abundance is significantly associated with the protein abundance of many other proteins, with 8,564 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KPTN-associated proteins across cancer lineages are ITFG2, DNAJC1, and AKR7A2. Each is linked with KPTN in more than 4 cancer types. Because this analysis shows association rather than direction, both KPTN-to-partner and partner-to-KPTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPTN versus ITFG2 in UCEC, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KPTN→partner) and Y-score (partner→KPTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ITFG2 →	+0.342	+0.433	<.001	<.001	3	5
BRCA	DNAJC1 →	-0.810	-0.411	<.001	<.001	3	4
CCRCC	AKR7A2 →	+0.265	+0.273	<.001	<.001	3	3
BRCA	TECR →	-0.443	-0.222	.001	.003	2	4
BRCA	TPI1 →	+0.371	+0.323	<.001	.001	3	3
OV	SPN →	-0.734	-0.505	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,564 associations by consensus.

KPTN vs ITFG2 — UCEC

Explore this scatter interactively →