KPTN

Across TCGA cell cohorts, KPTN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,077 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KPTN-associated GO terms across cancer lineages are Regulation of DNA repair, DNA-templated transcription initiation, and Regulation of double-strand break repair via homologous recombination. Each is linked with KPTN in more than 13 cancer types. Because this analysis shows association rather than direction, both KPTN-to-partner and partner-to-KPTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by KPTN-low versus KPTN-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KPTN→partner) and Y-score (partner→KPTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of DNA repair →	+0.058	+1.275	.005	.001	3	13
OESOPHAGUS	DNA-templated transcription initiation →	+0.069	+1.058	<.001	.001	2	14
BONE	Regulation of double-strand break repair via homologous recombination →	+0.106	+0.917	.003	<.001	3	12
LUNG_SCLC	Regulation of DNA recombination →	+0.072	+0.783	.005	.002	2	13
STOMACH	Import into nucleus →	+0.075	+1.288	<.001	<.001	3	12
LIVER	Positive regulation of transmembrane transport →	-0.077	-0.475	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

Regulation of DNA repair by KPTN expression — STOMACH

Explore this box plot interactively →