KPNB1

Across TCGA patient cohorts, KPNB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,327 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KPNB1-associated proteins across cancer lineages are RRM1, SMC2, and NCAPG. Each is linked with KPNB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both KPNB1-to-partner and partner-to-KPNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNB1 versus RRM1 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNB1→partner) and Y-score (partner→KPNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RRM1 →	+0.477	+0.311	<.001	<.001	3	9
GBM	SMC2 →	+0.750	+0.322	<.001	<.001	3	8
GBM	NCAPG →	+0.565	+0.256	<.001	.002	3	8
GBM	MCM3 →	+0.820	+0.289	<.001	.002	3	8
LUAD	NCAPG_S674 →	+0.889	+0.382	<.001	<.001	3	8
OV	CDC27 →	+0.302	+0.480	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,327 associations by consensus.

KPNB1 vs RRM1 — GBM

Explore this scatter interactively →