Across TCGA patient cohorts, KPNA7 protein abundance is significantly associated with the RNA expression of many other genes, with 308 significant associations in total. OV shows the largest number of these associations.

The most reproducible KPNA7-associated genes across cancer lineages are RIOK3, SUPT20H, and CLN5. Each is linked with KPNA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KPNA7-to-partner and partner-to-KPNA7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA7→partner) and Y-score (partner→KPNA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RIOK3 →	+0.582	+1.480	<.001	.002	3	1
OV	SUPT20H →	+0.691	+1.604	<.001	<.001	3	1
OV	CLN5 →	+0.835	+2.350	<.001	<.001	3	1
OV	CDR2L →	+1.334	+2.099	.005	<.001	3	1
OV	PDE8B →	+0.495	+1.660	.001	.007	3	1
OV	UPK1B →	+2.602	+1.352	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 308 associations by consensus.

Exploration

KPNA7 survival (RNA) · tumor vs normal (RNA) · all KPNA7 data types