KPNA4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KPNA4 mutation is significantly associated with the RNA expression of many other genes, with 6,861 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KPNA4-associated genes across cancer lineages are IGHD3-3, RNA5SP442, and ATXN7L3P1. Each is linked with KPNA4 in more than 2 cancer types. Because this analysis shows association rather than direction, both KPNA4-to-partner and partner-to-KPNA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA4→partner) and Y-score (partner→KPNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECIGHD3-3 →+1.048+1.458<.001<.00133
COADRNA5SP442 →+0.553+4.308<.001.00932
COADATXN7L3P1 →+0.128+3.717<.001.00832
COADLINC01066 →+0.218+5.824<.001.00132
COADCBX1P5 →+0.138+5.824<.001.00132
COADRPSAP35 →+0.098+6.568<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,861 associations by consensus.

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