Across TCGA cell cohorts, KPNA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,663 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KPNA4-associated GO terms across cancer lineages are Positive regulation of t-circle formation, Somatic cell DNA recombination, and Somatic diversification of immune receptors via germline recombination within a single locus. Each is linked with KPNA4 in more than 13 cancer types. Because this analysis shows association rather than direction, both KPNA4-to-partner and partner-to-KPNA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA4→partner) and Y-score (partner→KPNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of t-circle formation →	-0.153	-0.646	.002	.003	3	14
BREAST	Somatic cell DNA recombination →	+0.073	+0.516	.001	.008	3	13
BREAST	Somatic diversification of immune receptors via germline recombination within a single locus →	+0.073	+0.516	.001	.008	3	13
BLOOD_Myeloma	Positive regulation of mRNA processing →	+0.135	+0.940	<.001	<.001	3	13
LARGE_INTESTINE	Protein modification by small protein removal →	+0.041	+0.551	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of translational initiation →	+0.101	+0.584	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,663 associations by consensus.

Exploration

KPNA4 survival (RNA) · tumor vs normal (RNA) · all KPNA4 data types