KPNA3

Across TCGA patient cohorts, KPNA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,920 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KPNA3-associated proteins across cancer lineages are GTF2F1, GTF2F2, and SUGT1. Each is linked with KPNA3 in more than 5 cancer types. Because this analysis shows association rather than direction, both KPNA3-to-partner and partner-to-KPNA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNA3 versus GTF2F1 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA3→partner) and Y-score (partner→KPNA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GTF2F1 →	+0.286	+0.384	<.001	<.001	3	6
GBM	GTF2F2 →	+0.462	+0.601	<.001	<.001	3	6
COAD	SUGT1 →	+0.413	+0.477	<.001	<.001	3	6
PDAC	ITPR1 →	-0.388	-0.349	<.001	.002	3	5
COAD	HSPH1 →	+0.340	+0.296	<.001	<.001	3	4
HNSC	INTS1 →	+0.155	+0.519	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,920 associations by consensus.

KPNA3 vs GTF2F1 — GBM

Explore this scatter interactively →