KPNA3

Across TCGA patient cohorts, KPNA3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,012 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KPNA3-associated genes across cancer lineages are NUFIP1, MRPS31, and MED4. Each is linked with KPNA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both KPNA3-to-partner and partner-to-KPNA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNA3 versus NUFIP1 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA3→partner) and Y-score (partner→KPNA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NUFIP1 →	+0.505	+0.328	.002	<.001	3	8
UCEC	MRPS31 →	+0.510	+0.228	<.001	<.001	3	7
OV	MED4 →	+0.453	+0.248	.001	.002	3	7
COAD	GTF2F2 →	+0.631	+0.364	<.001	<.001	3	7
UCEC	VWA8 →	+0.724	+0.285	<.001	<.001	3	6
COAD	PROSER1 →	+0.795	+0.330	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,012 associations by consensus.

KPNA3 vs NUFIP1 — OV

Explore this scatter interactively →