KPNA2

Across TCGA patient cohorts, KPNA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,549 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KPNA2-associated proteins across cancer lineages are PTPN2_S304, PURA, and RPL12_S38. Each is linked with KPNA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both KPNA2-to-partner and partner-to-KPNA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNA2 versus PTPN2_S304 in OV, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA2→partner) and Y-score (partner→KPNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTPN2_S304 →	+0.889	+1.312	<.001	<.001	3	10
GBM	PURA →	-0.404	-0.676	<.001	<.001	3	10
LUAD	RPL12_S38 →	+1.417	+1.142	<.001	<.001	3	10
HNSC	RRM1 →	+0.500	+1.085	<.001	<.001	3	10
LUAD	RRM2 →	+0.977	+1.192	<.001	<.001	3	10
UCEC	SMC2 →	+0.719	+1.039	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,549 associations by consensus.

KPNA2 vs PTPN2_S304 — OV

Explore this scatter interactively →