KPNA2

Across TCGA patient cohorts, KPNA2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,798 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KPNA2-associated genes across cancer lineages are CENPM, CDKN3, and GINS1. Each is linked with KPNA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both KPNA2-to-partner and partner-to-KPNA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNA2 versus CENPM in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA2→partner) and Y-score (partner→KPNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPM →	+1.591	+0.527	<.001	<.001	3	10
LUAD	CDKN3 →	+1.431	+0.768	<.001	<.001	3	10
LUAD	GINS1 →	+1.334	+0.753	<.001	<.001	3	10
LUAD	MYBL2 →	+1.975	+0.725	<.001	<.001	3	10
LUAD	CENPI →	+1.304	+0.753	<.001	<.001	3	10
OV	MCM4 →	+1.103	+0.670	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,798 associations by consensus.

KPNA2 vs CENPM — UCEC

Explore this scatter interactively →