KPNA2

Across TCGA cell cohorts, KPNA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,209 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KPNA2-associated GO terms across cancer lineages are Spindle elongation, Kinetochore assembly, and DNA replication. Each is linked with KPNA2 in more than 18 cancer types. Because this analysis shows association rather than direction, both KPNA2-to-partner and partner-to-KPNA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by KPNA2-low versus KPNA2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA2→partner) and Y-score (partner→KPNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Spindle elongation →	+0.291	+1.472	<.001	<.001	3	19
OESOPHAGUS	Kinetochore assembly →	+0.222	+1.347	<.001	<.001	3	19
BLOOD_Myeloma	DNA replication →	+0.113	+1.108	<.001	<.001	3	19
BLOOD_Myeloma	DNA-templated DNA replication →	+0.123	+1.249	<.001	<.001	3	19
OESOPHAGUS	Regulation of mitotic nuclear division →	+0.161	+1.210	.001	.001	3	19
UPPER_AERODIGESTIVE_TRACT	Replication fork processing →	+0.130	+1.658	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,209 associations by consensus.

Spindle elongation by KPNA2 expression — URINARY_TRACT

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